Publications
Shaping the host cell environment with viral noncoding RNAs
Gorbea C, Elhakiem A, Cazalla D.
Semin Cell Dev Biol. 2022 Dec 27:S1084-9521(22)00376-7.
PMID: 36581481
Allosteric regulation of noncoding RNA function by microRNAs
Gorbea C, Elhakiem A, Cazalla D.
Nucleic Acids Res. 2022 Jun 24;50(11):6511-6520.
PMID: 35648438
Learning noncoding RNA biology from viruses.
Cazalla D.
Mamm Genome. 2021 Sep 7. doi: 10.1007/s00335-021-09915-y. Online ahead of print.
PMID: 34491378 Review.
Viral miRNA adaptor differentially recruits miRNAs to target mRNAs through alternative base-pairing.
Gorbea C, Mosbruger T, Nix DA, Cazalla D.
Elife. 2019 Sep 20;8. pii: e50530
PMID: 31538617
Differential transcriptional profiles identify microglial- and macrophage-specific gene markers expressed during virus-induced neuroinflammation.
DePaula-Silva AB, Gorbea C, Doty DJ, Libbey JE, Sanchez JMS, Hanak TJ, Cazalla D, Fujinami RS.
J Neuroinflammation. 2019 Jul 20;16(1):152. doi: 10.1186/s12974-019-1545-x.
PMID: 31325960
Novel roles for Sm-class RNAs in the regulation of gene expression.
Cazalla D.
RNA Biol. 2018 Jul 9:1-7. doi: 10.1080/15476286.2018.1467176. [Epub ahead of print]
PMID: 29895222
A viral Sm-class RNA base-pairs with mRNAs and recruits microRNAs to inhibit apoptosis.
Gorbea C, Mosbruger T, Cazalla D.
Nature. 2017 Oct 12;550(7675):275-279. doi: 10.1038/nature24034. Epub 2017 Oct 4.
PMID: 28976967
MicroRNA-9 controls dendritic development by targeting REST.
Giusti SA, Vogl AM, Brockmann MM, Vercelli CA, Rein ML, Trümbach D, Wurst W, Cazalla D, Stein V, Deussing JM, Refojo D.
Elife. 2014 Nov 18;3:e02755. doi: 10.7554/eLife.02755.
PMID: 25406064
RNase III-independent microRNA biogenesis in mammalian cells
Maurin T, Cazalla D, Yang S Jr, Bortolamiol-Becet D, Lai EC.
RNA. 2012 Dec;18(12):2166-73.
PMID: 23097423
A primate herpesvirus uses the integrator complex to generate viral microRNAs.
Cazalla D, Xie M, Steitz JA.
Mol Cell. 2011 Sep 16;43(6):982-92. doi: 10.1016/j.molcel.2011.07.025.
PMID: 21925386
miR-29 and miR-30 regulate B-Myb expression during cellular senescence
Martinez I, Cazalla D, Almstead LL, Steitz JA, DiMaio D.
Proc Natl Acad Sci U S A. 2011 Jan 11;108(2):522-7.
PMID: 21187425
Down-regulation of a host microRNA by a viral noncoding RNA
Cazalla D, Steitz JA.
Cold Spring Harb Symp Quant Biol. 2010;75:321-4.
PMID: 21139068
Noncoding RNPs of viral origin.
Steitz J, Borah S, Cazalla D, Fok V, Lytle R, Mitton-Fry R, Riley K, Samji T.
Cold Spring Harb Perspect Biol. 2011 Mar 1;3(3). doi:pii: a005165. 10.1101/cshperspect.a005165. Review.
PMID: 20719877
Down-regulation of a host microRNA by a Herpesvirus saimiri noncoding RNA.
Cazalla D, Yario T, Steitz JA.
Science. 2010 Jun 18;328(5985):1563-6.
PMID: 20558719
The challenge of viral snRNPs
Conrad NK, Fok V, Cazalla D, Borah S, Steitz JA.
Cold Spring Harb Symp Quant Biol. 2006;71:377-84.
PMID: 17381320
Reversible phosphorylation differentially affects nuclear and cytoplasmic functions of splicing factor 2/alternative splicing factor
Sanford JR, Ellis JD, Cazalla D, Cáceres JF.
Proc Natl Acad Sci U S A. 2005 Oct 18;102(42):15042-7.
PMID: 16210245
A rapid and efficient protocol to purify biologically active recombinant proteins from mammalian cells
Cazalla D, Sanford JR, Cáceres JF.
Protein Expr Purif. 2005 Jul;42(1):54-8.
PMID: 15878828
A novel SR-related protein is required for the second step of Pre-mRNA splicing
Cazalla D, Newton K, Cáceres JF.
Mol Cell Biol. 2005 Apr;25(8):2969-80.
PMID: 15798186
Nuclear export and retention signals in the RS domain of SR proteins
Cazalla D, Zhu J, Manche L, Huber E, Krainer AR, Cáceres JF.
Mol Cell Biol. 2002 Oct;22(19):6871-82.
PMID: 12215544
Antagonistic effects of T-Ag and VP16 reveal a role for RNA pol II elongation on alternative splicing
Kadener S, Cramer P, Nogués G, Cazalla D, de la Mata M, Fededa JP, Werbajh SE, Srebrow A, Kornblihtt AR.
EMBO J. 2001 Oct 15;20(20):5759-68.
PMID: 11598018
Coupling of transcription with alternative splicing: RNA pol II promoters modulate SF2/ASF and 9G8 effects on an exonic splicing enhancer
Cramer P, Cáceres JF, Cazalla D, Kadener S, Muro AF, Baralle FE, Kornblihtt AR.
Mol Cell. 1999 Aug;4(2):251-8.
PMID: 10488340
Evidence of genetic heterogeneity in a BALB/c mouse colony as determined by DNA fingerprinting
Benavides F, Cazalla D, Pereira C, Fontanals A, Salaverri M, Goldman A, Buggiano V, Dran G, Corley E.
Lab Anim. 1998 Jan;32(1):80-5.
PMID: 9481698